Impacto del ácido acetilsalicílico en la producción y bienestar avícola: Revisión sistemática
Palabras clave:
Bienestar animal, parámetros productivos, producción avícolaResumen
DOI: https://doi.org/10.46296/gt.v8i16.0270
Resumen
La creciente preocupación por la resistencia de antibióticos en la producción avícola, ha motivado a la búsqueda de alternativas para la mejora de la salud y la productividad de los pollos de engorde. El estudio tiene el objetivo de evaluar el impacto del uso del ácido acetilsalicílico (ASA) en producciones avícolas. Para su cumplimiento, se desarrolló una revisión bibliográfica sistemática con el enfoque metodológico PRISMA, para la recopilación de los antecedentes investigativos, se usó bases de datos científicas de alto impacto, como Scopus, Taylor y Francis, PubMed y Science Direct, la selección de estudios se realizó bajo criterios de inclusión y exclusión y sus resultados se organizaron de manera descriptiva en un esquema resumido. Los resultados muestran que dosis de mínimas y moderadas de ASA influyen positivamente en parámetros productivos como el peso y la conversión de alimento, al mismo tiempo que mejoran la salud general, la respuesta inmunológica y la resistencia al estrés de las aves. En contraste, las dosis altas, se asociaron con efectos adversos, incluyendo alteraciones hepáticas, renales y compromiso de la respuesta inmunológica. En general, el ASA es una alternativa adecuada para optimizar la producción avícola, siempre que se respeten los rangos de dosificación adecuados.
Palabras claves: Bienestar animal, parámetros productivos, producción avícola.
Abstract
Growing concern about antibiotic resistance in poultry production has prompted the search for alternatives to improve the health and productivity of broiler chickens. The study aims to evaluate the impact of acetylsalicylic acid (ASA) use in poultry production. To this end, a systematic literature review was conducted using the PRISMA methodological approach. High-impact scientific databases such as Scopus, Taylor and Francis, PubMed, and Science Direct were used to compile the research background. Studies were selected based on inclusion and exclusion criteria, and the results were organized descriptively in a summary outline. The results show that minimal and moderate doses of ASA positively influence production parameters such as weight and feed conversion, while improving the overall health, immune response, and stress resistance of the birds. In contrast, high doses were associated with adverse effects, including liver and kidney disorders and compromised immune response. In general, ASA is a suitable alternative for optimizing poultry production, provided that the appropriate dosage ranges are respected.
Keywords: Animal welfare, production parameters, poultry production.
Información del manuscrito:
Fecha de recepción: 13 de junio de 2025.
Fecha de aceptación: 29 de agosto de 2025.
Fecha de publicación: 22 de septiembre de 2025.
Descargas
Citas
Alagawany, M., Farag, El-Hack, M. A., Dhama, K., & Fowler, J. (2017). Use of acetylsalicylic acid as a feed additive in poultry nutrition. World's Poultry Science Journal, 73(3), 633–642. https://doi.org/10.1017/s0043933917000253
Apalowo, O., Ekunseitan, D., & Fasina, Y. (2024). Impact of heat stress on broiler chicken production. Poultry, 3(2), 107–128. https://doi.org/10.3390/poultry3020010
Ayana, G. U., & Kamutambuko, R. (2024). Probiotics in Disease Management for Sustainable Poultry Production. Advanced Gut & Microbiome Research, 2024(1). https://doi.org/10.1155/2024/4326438
Azabache C., (2012). Efecto de la adición de vitamina C (ácido ascórbico) y aspirina (ácido acetilsalicílico) en la performance de pollos de carne en fase de acabado. Yurimaguas. https://biblioteca.unapiquitos.edu.pe/bib/17528
Biagini, L., Galosi, L., Roncarati, A., Attili, A., Mangiaterra, S., & Rossi, G. (2022). The role of nutraceuticals and phytonutrients in chickens’ gastrointestinal diseases. Animals, 12(7), 892. https://doi.org/10.3390/ani12070892
Derakhshanfar, A., Kheirandish, R., Alidadi, S., & Bidadkosh, A. (2012). Study of long effects of administration of aspirin (acetylsalicylic acid) on bone in broiler chickens. Comparative Clinical Pathology, 22(6), 1201–1204. https://doi.org/10.1007/s00580-012-1550-2
Fathi, M., & Haydari, M. (2016). Influence of Dietary Aspirin on Growth Performance, Antioxidant Status, and Mortality due to Ascites in Broiler Chickens. DOAJ (DOAJ: Directory of Open Access Journals). https://doi.org/10.22069/psj.2016.10701.1178
Fathi, M., & Mardani, P. (2024). Stress in broiler farming. In IntechOpen eBooks. https://doi.org/10.5772/intechopen.1005612
Ferronato, G., Tavakoli, M., Bouyeh, M., Seidavi, A., Ramírez, L. S., & Prandini, A. (2024). Effects of combinations of dietary vitamin C and acetylsalicylic acid on growth performance, carcass traits and serum and immune response parameters in broilers. Animals, 14(4), 649. https://doi.org/10.3390/ani14040649
Gualoto, L. (2013). Efecto del Uso de Ácido Acetilsalicílico, Suministrado en el Balanceado, para Evitar Muertes por Estrés Calórico, en la Producción de Pollos Broilers. [Tesis de pregrado, Escuela Superior Politécnica de Chimborazo]. Repositorio institucional. https://dspace.espoch.edu.ec/handle/123456789/3120
Güngören, G., Demircioğlu, İ., Şimşek, Ü. G., Keskinbıçak, Y., Akarsu, S., & Kanik, B. (2024). Effect of acetylsalicylic acid application on GAIT score and femur osteometry in broiler chickens. Harran Üniversitesi Veteriner Fakültesi Dergisi. https://doi.org/10.31196/huvfd.1561191
Haddaway, N., Page, M., Pritchard, C., & McGuinness, L. (2022). PRISMA2020: An R package and Shiny app for producing PRISMA 2020‐compliant flow diagrams, with interactivity for optimised digital transparency and Open Synthesis. Campbell Systematic Reviews, 18(2). https://doi.org/10.1002/cl2.1230
Hassan, A., & Asim, R. (2020). Effect of vitamin C and acetylsalicylic acid supplementation on some hematological value, heat shock protein 70 concentration and growth hormone level in broiler exposed to heat stress. Journal of Veterinary Sciences, 34(2), 357–363. https://doi.org/10.33899/ijvs.2019.125950.1195
Hormozi, M., & Jahantigh, M. (2017). The effect of acetylsalicylic acid and berberis on ascites syndrome parameters in broiler chickens. PubMed, 20(4), 835–837. https://doi.org/10.1515/pjvs-2017-0107
Jaramillo, S. (2023). Biosecurity: A holistic One-Health concept for enhancing the health, welfare, and productivity of commercial poultry - A point of view. Proceeding of The First International Avian Influenza Summit, University of Arkansas- October 16-17, 2023”. GMPC Thesis & Opinions Platform, 3(1), 24. https://doi.org/10.51585/gtop.2023.1.0027
Jebur, S., Mohammed, T., & Al-Khalani, F. (2018). Effect of vitamin E, C and aspirin in the performance, lipid peroxidation and blood biochemistry traits of broiler in heat stress. The Eurasia Proceedings of Science Technology Engineering and Mathematics, 3, 145–151. https://dergipark.org.tr/tr/download/article-file/586779
Loor, C., Lara, M., y Robalino, C. (2024). Ácido acético como aditivo alimentario para mejorar el rendimiento productivo en pollos Cobb 500. Revista Alfa, 8(24), 1042–1055. https://doi.org/10.33996/revistaalfa.v8i24.322
Mahasneh, Z., Abuajamieh, M., Abedal, M., Al-Qaisi, M., Abdelqader, A., & Al-Fataftah, A. (2024). Effects of medical plants on alleviating the effects of heat stress on chickens. Poultry Science, 103(3), 103391. https://doi.org/10.1016/j.psj.2023.103391
Mohan, K., Jayakumar, K., Narayanaswamy, H., Pavithra, B., & Bayer, M. (2012). Study of potential toxic effects of acetylsalicylic acid upon short-term repeated oral administration in chickens. Journal of Applied Animal Research, 40(4), 330–335. https://doi.org/10.1080/09712119.2012.692328
Muneeb, M., Javed, M., Sarfaraz, T., Ayub, A., Israr, F., Anwar, S., Abdeen, Z. ul, Hina, I., Raza, A., Afzal, Z., Zarnab, S., & Ali, M. (2022). Effects of different acetylsalicylic acid doses on body organs, histopathology, and serum biochemical parameters in broiler birds. Brazilian Journal of Veterinary Research and Animal Science, 59, e176998. https://doi.org/10.11606/issn.1678-4456.bjvras.2022.176998
Naseem, M. Younus, A., Aamir, Asim, & S. Akhter. (2005). Effect of Ascorbic Acid and Acetylsalicylic Acid Supplementation on Performance of Broiler Chicks Exposed to Heat Stress. International Journal of Poultry Science, 4(11), 900-904. https://doi.org/10.3923/ijps.2005.900.904
Pagano, M., Savoca, S., Impellitteri, F., Albano, M., Capillo, G., & Faggio, C. (2022). Toxicological Evaluation of Acetylsalicylic Acid in Non-Target Organisms: Chronic Exposure on Mytilus galloprovincialis (Lamarck, 1819). Frontiers in Physiology, 13. https://doi.org/10.3389/fphys.2022.920952
Pashaei, M., Fayçal, Z., Kahrizi, D., & Ercisli, S. (2024). Medicinal Plants and Natural Substances for Poultry Health: A review. Journal of Poultry Sciences and Avian Diseases, 2(2), 36–49. https://doi.org/10.61838/kman.jpsad.2.2.5
Poźniak, B., Świtała, M., Bobrek, K., Graczyk, S., & Dzimira, S. (2012). Adverse effects associated with high-dose acetylsalicylic acid and sodium salicylate treatment in broilers. British Poultry Science, 53(6), 777–783. https://doi.org/10.1080/00071668.2012.745929
Proudfoot, F., & Hulan, H. (1983). Effects of dietary aspirin (acetylsalicylic acid) on the incidence of sudden death syndrome and the general performance of broiler chickens. Canadian Journal of Animal Science, 63(2), 469–471. https://doi.org/10.4141/cjas83-056
Ravi, R., & Golder, A. K. (2023). Pharmaceutically Active Compounds’ (PHACs) threat: an environmental prospective. In Sustainable Environment (pp. 51-66). https://doi.org/10.1007/978-981-19-8464-8_3
Rincón, F., Hurtado, E., Robalino, C., y Aguilar, P. (2024). Gums exudates of Prosopis spp. located in Ecuador: prebiotic potential in animal feed. Revista De La Facultad De Agronomía, 41(4), e244139. https://doi.org/10.47280/revfacagron(luz).v41.n4.08
Tavakoli, M., Bouyeh, M., & Seidavi, A. (2021). Effects of Dietary Aspirin Supplementation on Growth Performance, Carcass Characteristics, Gastrointestinal Organs and Liver Enzymes, Abdominal Fats, Immune Response, Cecum Microflora and Fatty Acid Profile in Breast Meat of Broiler Chickens. Research Square (Research Square). https://doi.org/10.21203/rs.3.rs-435345/v1
Tavakoli, M., Bouyeh, M., & Seidavi, A. (2023). Influences of dietary aspirin supplementation on growth performance, carcass characteristics and gastrointestinal organs of broilers. Journal of the Hellenic Veterinary Medical Society, 73(4), 5061–5066. https://doi.org/10.12681/jhvms.27696
Téllez, G., Eisenreich, W., Petrone, V., Hernandez, X., Castellanos, C., Tellez, G., Latorre, J., Bottje, W., Senas, R., Coles, M., Hargis, B., El-Ashram, S., Graham, B., & Shehata, A. (2023). Effects of chronic stress and intestinal inflammation on commercial poultry health and performance: A review. German Journal of Veterinary Research, 3(1), 38–57. https://doi.org/10.51585/gjvr.2023.1.0051
Torres, M., Cevallos, M. y Briones, C. (2024). Probióticos: su efecto en el tracto intestinal de pollos de engorde. Revista Alfa, 8(24), 737–746. https://doi.org/10.33996/revistaalfa.v8i24.299
Wolf, T., Toppel, K., Jacobsen, L., Andersson, R., & Touma, C. (2024). Measuring urofecal glucocorticoid metabolites in broiler chickens: a noninvasive tool for assessing stress as a marker of welfare. Poultry Science, 103(11), 104162. https://doi.org/10.1016/j.psj.2024.104162.
Zambrano, E. (2016). Ácido acetilsalicílico y vitamina C en el comportamiento productivo en pollos de engorde COBB 500 en la ESPAM MFL. [Tesis de pregrado, Escuela Superior Politécnica Agropecuaria de Manabí]. Repositorio Institucional. https://repositorio.espam.edu.ec/handle/42000/590
Publicado
Cómo citar
Número
Sección
Derechos de autor 2025 Revista Científica Arbitrada en Investigaciones de la Salud GESTAR. ISSN: 2737-6273.
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0.
